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Tigecycline has unstable physicochemical properties and is prone to lose its antibacterial activity under light conditions. After adding copper ions, the antibacterial activity of tigecycline under light conditions is significantly enhanced.

ABSTRACT: Tigecycline, as a new type of tetracycline antibiotic, has unstable physicochemical properties. When exposed to light, it easily loses its antibacterial activity. This study found that after adding copper ions, the antibacterial activity of tigecycline under light conditions was significantly enhanced.

ORGANISM(S): Escherichia Coli

SUBMITTER: Yonglin Zhou

PROVIDER: PXD077522 | iProX | Thu Apr 23 00:00:00 BST 2026

REPOSITORIES: iProX

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