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Proteomic profiling of multiple neural and peripheral tissues in a mouse model of trigeminal neuralgia

ABSTRACT: This project aims to characterize the proteomic alterations in four significant tissues—liver, infraorbital nerve, trigeminal ganglion, and spinal trigeminal nucleus caudalis—in a mouse model of trigeminal neuralgia induced by partial infraorbital nerve ligation (pIONL). Using a label-free quantitative proteomics approach, we compared pIONL mice with sham-operated controls. The data provide tissue-specific protein expression signatures associated with peripheral nerve injury, central pain processing, and systemic metabolic responses.

ORGANISM(S): Mus Musculus

SUBMITTER: Chaoli Hong

PROVIDER: PXD077570 | iProX | Fri Apr 24 00:00:00 GMT+01:00 2026

REPOSITORIES: iProX

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