Identification of the direct molecular target of sanguinarine in bladder cancer cells
Ontology highlight
ABSTRACT: Sanguinarine possesses anticancer, antioxidant activities; however, its direct target(s) and mechanism of action have long remained unclear, limiting its translational and clinical application. Here, we employed limited proteolysis-coupled mass spectrometry (LiP-MS) to identify its direct target(s) in the T24 bladder cancer cell line, thereby providing a theoretical basis for further clinical development.
ORGANISM(S): Homo Sapiens
SUBMITTER:
Dahong Zhang
PROVIDER: PXD078043 | iProX | Fri May 01 00:00:00 BST 2026
REPOSITORIES: iProX
ACCESS DATA