Proteomics

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Identification of the direct molecular target of sanguinarine in bladder cancer cells


ABSTRACT: Sanguinarine possesses anticancer, antioxidant activities; however, its direct target(s) and mechanism of action have long remained unclear, limiting its translational and clinical application. Here, we employed limited proteolysis-coupled mass spectrometry (LiP-MS) to identify its direct target(s) in the T24 bladder cancer cell line, thereby providing a theoretical basis for further clinical development.

ORGANISM(S): Homo Sapiens

SUBMITTER: Dahong Zhang  

PROVIDER: PXD078043 | iProX | Fri May 01 00:00:00 BST 2026

REPOSITORIES: iProX

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