Dataset Information
Comprehensive analyses of the macrophages infected with avirulent and virulent Mycobacterium tuberculosis strains uncover distinct immune mechanisms and anti-TB effect of treated exosomes
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Fei Chen
PROVIDER: PXD078478 | iProX | Mon May 18 00:00:00 GMT+01:00 2026
REPOSITORIES: iProX
Publications
Macrophage Response to Avirulent and Virulent Mycobacterium tuberculosis and Anti-TB Effects of Exosome Treatment.
Genomics, proteomics & bioinformatics 20251201 6
Tuberculosis (TB) has returned as the leading cause of death caused by a single infectious agent in 2023. Human macrophages and their secreted exosomes play important roles in combating invading Mycobacterium tuberculosis (Mtb). However, a comprehensive understanding of the mechanisms underlying immune regulation in Mtb-infected macrophages, as well as the packaging mechanisms and anti-TB effects of Mtb-treated exosomes, is still lacking. Here, we conducted comprehensive analyses of the macropha ...[more]
