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P53 mutant dislodges BRCA2 from chromatin and induces R-loop accumulation

ABSTRACT: To investigate the mechanism underlying R-loop accumulation, we conducted a BioID proximity-labeling assays using BioID-tagged p53-WT and p53-R273H, followed by mass spectrometry detection.

ORGANISM(S): Homo Sapiens

SUBMITTER: Zhuojuan Luo

PROVIDER: PXD078710 | iProX | Fri May 22 00:00:00 GMT+01:00 2026

REPOSITORIES: iProX

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