Proteomics

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Lactylation of histone variant MacroH2A1 at K134 regulates osteogenic differentiation of bone marrow mesenchymal stem cells


ABSTRACT: Although lactate is linked to osteoporosis pathogenesis, the role of protein lactylation in MSC osteogenic differentiation remains unelucidated. This study explored protein lactylation during early MSC osteogenic differentiation, focusing on histone variant MacroH2A1.

ORGANISM(S): Homo Sapiens

SUBMITTER: Jianjun Xiong  

PROVIDER: PXD078798 | iProX | Sun May 24 00:00:00 GMT+01:00 2026

REPOSITORIES: iProX

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