Proteomics

Dataset Information

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Proteomic Dataset of Rat Pulmonary Arteries in a Magnesium-Treated PAH Model


ABSTRACT: This project investigates the role of magnesium-induced phase separation of UBXN1 protein in the pathogenesis of pulmonary arterial hypertension (PAH). We aim to elucidate the molecular mechanism by which magnesium promotes UBXN1 condensation and affects PAH-related signaling pathways, using both cellular models and animal experiments. Our findings may provide new insights into the therapeutic targeting of phase separation in vascular diseases.

ORGANISM(S): Rattus Norvegicus

SUBMITTER: Jiayu Liu  

PROVIDER: PXD080220 | iProX | Fri Jun 26 00:00:00 GMT+01:00 2026

REPOSITORIES: iProX

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