Dataset Information
BAZ1A/B proteomics
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Shinya Ohta
PROVIDER: PXD008696 | JPOST Repository | Sun Oct 07 00:00:00 BST 2018
REPOSITORIES: jPOST
Publications
Quantitative Proteomics of the Mitotic Chromosome Scaffold Reveals the Association of BAZ1B with Chromosomal Axes.
Molecular & cellular proteomics : MCP 20180928 2
In mitosis, chromosomes achieve their characteristic shape through condensation, an essential process for proper segregation of the genome during cell division. A classical model for mitotic chromosome condensation proposes that non-histone proteins act as a structural framework called the chromosome scaffold. The components of the chromosome scaffold, such as DNA topoisomerase IIα (TOP2A) and structural maintenance of chromosomes protein 2 (SMC2), are necessary to generate stable mitotic chromo ...[more]
