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KAP3 kinase assay

ABSTRACT: Phosphoproteomic analysis of recombinant KAP3 reacted with MARK2 kinase in vitro.

ORGANISM(S): Mus Musculus (mouse)

SUBMITTER: Nobutaka Hirokawa

PROVIDER: PXD014110 | JPOST Repository | Thu Aug 29 00:00:00 BST 2019

REPOSITORIES: jPOST

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			Action	DRS
	KAP.mgf	Mgf
	KAP.raw	Raw
	Select%20Summary%20Report%20(__-data-20170628-F020860_dat).htm	Other

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Publications

The Spatiotemporal Construction of the Axon Initial Segment via KIF3/KAP3/TRIM46 Transport under MARK2 Signaling.

Ichinose Sotaro S Ogawa Tadayuki T Jiang Xuguang X Hirokawa Nobutaka N

Cell reports 20190801 9

The axon initial segment (AIS) is a compartment that serves as a molecular barrier to achieve axon-dendrite differentiation. Distribution of specific proteins during early neuronal development has been proposed to be critical for AIS construction. However, it remains unknown how these proteins are specifically targeted to the proximal axon within this limited time period. Here, we reveal spatiotemporal regulation driven by the microtubule (MT)-based motor KIF3A/B/KAP3 that transports TRIM46, inf ...[more]

PMID: 31461655

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