Integrated proteomics and phosphoproteomics analyses reveal the broad and complex influence by inhibition of L-type amino acid transporter-1 in biliary tract carcinoma cells

ABSTRACT: To characterize the changes of phosphorylation signaling cascades and protein expressions induced by LAT1 inhibition in 4 cell lines of biliary tract cancer treated with LAT1 specific inhibitor JPH203, immobilized metal affinity chromatography and liquid chromatography-tandem mass spectrometry with MS2-based quantitation of tandem mass tag were utilized.

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Yoshikatsu Kanai 

PROVIDER: PXD019458 | JPOST Repository | Fri Dec 25 00:00:00 GMT 2020

REPOSITORIES: jPOST