Proteomics

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ROR1 sustains multivesicular endosomes by interacting with HRS and STAM1


ABSTRACT: The receptor tyrosine kinase-like orphan receptor 1 (ROR1) regulates caveolae formation and caveolae-dependent endocytosis by interacting with caveolae components, which in turn sustains pro-survival signaling toward AKT from multiple RTKs, including EGFR, and MET. We report here a novel function of ROR1 as a scaffold for HRS and STAM1, two essential components of ESCRT-0.

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Tomoya Yamaguchi 

PROVIDER: PXD020931 | JPOST Repository | Thu May 27 00:00:00 BST 2021

REPOSITORIES: jPOST

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