Proteomics

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KH: Investigation of mouse amniotic fluid for stimulating ability of keratinocyte differentiation depending on the fetal stage


ABSTRACT: Investigation of mouse amniotic fluid for stimulating ability of keratinocyte differentiation depending on the fetal stage

ORGANISM(S): Mus Musculus (mouse)

SUBMITTER: Kiyotaka Hitomi 

PROVIDER: PXD024377 | JPOST Repository | Thu Apr 13 00:00:00 BST 2023

REPOSITORIES: jPOST

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Investigation of mouse amniotic fluid for stimulating ability of keratinocyte differentiation depending on the fetal stage.

Kuribayashi Miki M   Kawaguchi Yusuke Y   Teshima Hirofumi H   Yamaguchi Hisateru H   Tatsukawa Hideki H   Hitomi Kiyotaka K  

Archives of biochemistry and biophysics 20210812


During fetal development, the barrier function of the fetal skin is developed under specific conditions for epidermis formation. In keratinocyte differentiation, the well-orchestrated production and modification of various structural proteins are induced. We assessed the epidermal barrier function in different fetal stages by evaluating the enzymatic activity of cross-linking proteins, transglutaminases, and the permeation of fluorescence dye in the stained epidermal sections. During days 15.5-1  ...[more]

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