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Sera Protein Signatures of Endometrial Cancer Lymph Node Metastases

ABSTRACT: sera collected from endometrial cancer patients submitted to direct MS/MS analysis in diluted unprocessed form. MS only analysis of sera has also been performed. files are also available.

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Jay Hanas & Doris Mangiaracina Benbrook

PROVIDER: PXD031892 | JPOST Repository | Thu Mar 17 00:00:00 GMT 2022

REPOSITORIES: jPOST

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Sera Protein Signatures of Endometrial Cancer Lymph Node Metastases.

Benbrook Doris Mangiaracina DM Hocker James Randolph Sanders JRS Moxley Katherine Marie KM Hanas Jay S JS

International journal of molecular sciences 20220318 6

The presence of lymph node metastases in endometrial cancer patients is a critical factor guiding treatment decisions; however, surgical and imaging methods for their detection are limited by morbidity and inaccuracy. To determine if sera can predict the presence of positive lymph nodes, sera collected from endometrial cancer patients with or without lymph node metastases, and benign gynecology surgical patients (N = 20 per group) were subjected to electron spray ionization mass spectrometry (ES ...[more]

PMID: 35328698

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