Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: W. Andy Tao
PROVIDER: PXD036956 | JPOST Repository | Thu Nov 10 00:00:00 GMT 2022
REPOSITORIES: jPOST
Kao Der-Shyang DS Du Yanyan Y DeMarco Andrew G AG Min Sehong S Hall Mark C MC Rochet Jean-Christophe JC Tao W Andy WA
Molecular & cellular proteomics : MCP 20221113 12
Hyperphosphorylation of the microtubule-associated protein Tau is a major hallmark of Alzheimer's disease and other tauopathies. Understanding the protein kinases that phosphorylate Tau is critical for the development of new drugs that target Tau phosphorylation. At present, the repertoire of the Tau kinases remains incomplete, and methods to uncover novel upstream protein kinases are still limited. Here, we apply our newly developed proteomic strategy, fluorescence complementation mass spectrom ...[more]