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Utilizing MALDI-TOF mass spectrometry and liquid chromatography-tandem mass spectrometry to access serum peptidome-based biomarkers in canine oral tumors

ABSTRACT: Tumors frequently found in dogs include canine oral tumors, either cancerous or noncancerous. The bloodstream is an important route for tumor metastasis, particularly for late-stage oral melanoma (LOM) and late-stage oral squamous cell carcinoma (LOSCC). The present study aimed to investigate serum peptidome-based biomarkers of dogs with early-stage oral melanoma, LOM, LOSCC, benign oral tumors, chronic periodontitis and healthy controls, using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and liquid chromatography tandem mass spectrometry.

ORGANISM(S): Cellular Organisms

SUBMITTER: Sittiruk Roytrakul

PROVIDER: PXD037051 | JPOST Repository | Thu Sep 28 00:00:00 BST 2023

REPOSITORIES: jPOST

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