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Gene expression profile of epithelial cells from five regions of human intestinal.

ABSTRACT: Data independent analysis of proteome of patient derived epithelial cell from five regions, duodenum, jejunum, ileum, colon and rectum.

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Takuma Katayama

PROVIDER: PXD037197 | JPOST Repository | Mon May 08 00:00:00 BST 2023

REPOSITORIES: jPOST

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			Action	DRS
	20210825_GPF_Biopsy_1.raw	Raw
	20210825_GPF_Biopsy_2.raw	Raw
	20210825_GPF_Biopsy_3.raw	Raw
	20210825_GPF_Biopsy_4.raw	Raw
	20210825_GPF_Biopsy_5.raw	Raw

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Publications

Regional Transcriptomics and Proteomics of Pharmacokinetics-Related Genes in Human Intestine.

Murata Michika M Fujioka Hijiri H Yokota Jumpei J Okada Kentaro K Yamashita Tomoki T Hirayama Daisuke D Kawakami Kentaro K Morinaga Gaku G Saito Asami A Nakase Hiroshi H Kishimoto Wataru W Mizuguchi Hiroyuki H

Molecular pharmaceutics 20230503 6

The intestine is an organ responsible for the absorption and metabolism of orally administered drugs. To predict pharmacokinetics behavior in the small intestine, it is necessary to examine the human intestinal expression profiles of the genes related to drug absorption, distribution, metabolism, and excretion (ADME). In this study, to obtain more accurate expression profiles in various regions of the human intestine, biopsy samples were collected from endoscopically noninflamed mucosa of the du ...[more]

PMID: 37132462

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