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Protein profiling of cerebrospinal fluid exracellular vesiles

ABSTRACT: Protein profiling of extracellular vesicle from cerebrospinal fluid of multiple sclerosis

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Shin Hisahara

PROVIDER: PXD047351 | JPOST Repository | Tue Sep 02 00:00:00 BST 2025

REPOSITORIES: jPOST

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	220805_MS_11.raw	Raw
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	220805_MS_6.raw	Raw
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Publications

Elevated ITGAX/CD11c in CSF-Derived Extracellular Vesicles Reflects Disability Progression in Multiple Sclerosis.

Iwahara Naotoshi N Muraoka Satoshi S Saito Taro T Hirano Masayo M Yokokawa Kazuki K Tanemoto Masanobu M Oda Ryosuke R Nonaka Takayuki T Suzuki Shuuichirou S Adachi Jun J Hisahara Shin S

Neurology(R) neuroimmunology & neuroinflammation 20250718 5

<h4>Background and objectives</h4>Extracellular vesicles (EVs) are membrane-bound particles that are released into the extracellular space and are believed to play a role in the pathogenesis of neuroinflammation and neurodegeneration. Nevertheless, the precise role of these vesicles in the context of multiple sclerosis (MS) remains uncertain. The objective of this study was to identify the distinctive characteristics of EVs associated with MS.<h4>Methods</h4>EVs were isolated from CSF using phos ...[more]

PMID: 40680248

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