Dataset Information
IP-MS analysis of HSF5 in mice
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus (mouse)
SUBMITTER: Kei-ichiro Ishiguro
PROVIDER: PXD051085 | JPOST Repository | Fri Mar 29 00:00:00 GMT 2024
REPOSITORIES: jPOST
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| a_1_HSF5_N1_IP.raw | Raw | |||
| a_1_HSF5_N1_IP.xlsx | Xlsx | |||
| a_2_HSF5_N2_IP.raw | Raw | |||
| a_2_HSF5_N2_IP.xlsx | Xlsx | |||
| a_3_control_IgG_IP.raw | Raw |
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Publications
Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions.
Nature communications 20240429 1
Meiotic prophase progression is differently regulated in males and females. In males, pachytene transition during meiotic prophase is accompanied by robust alteration in gene expression. However, how gene expression is regulated differently to ensure meiotic prophase completion in males remains elusive. Herein, we identify HSF5 as a male germ cell-specific heat shock transcription factor (HSF) for meiotic prophase progression. Genetic analyzes and single-cell RNA-sequencing demonstrate that HSF5 ...[more]
