Proteomics

Dataset Information

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Exosomes analysis for identification of potential biomarkers of cholangiocarcinoma and drug targets identification: proteomic and metabolomic approaches


ABSTRACT: Exosomes are extracellular vesicles necessary for cell communication, including cancer cells. Tumor-derived exosomes have been essential in biomarker screening and also therapeutic targets. In the present study, we used proteomics and metabolomics approaches to investigate the CCA biomarkers and molecular targets action of atractylodin and β-eudesmol in the exosomes isolated from cell culture media. The exosomes were extracted from CCA cell lines (CL-6, HUCCT-1, and HUH28) and normal cell lines (MMNK-1) and were exposed to the test compounds.

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Wanna Chajaroenkul 

PROVIDER: PXD051383 | JPOST Repository | Sat Apr 12 00:00:00 BST 2025

REPOSITORIES: jPOST

Dataset's files

Source:
Action DRS
H28_100%25Et_48H_2.mzXML Mzxml
H28_100%25Et_48H_3.mzXML Mzxml
H28_At_IC25_24H_1.mzXML Mzxml
H28_At_IC25_24H_2.mzXML Mzxml
H28_At_IC25_24H_3.mzXML Mzxml
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