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IsoAsp analysis of bovine lens alpha-crystallin

ABSTRACT: Isomerization of Asp residues has been long thought to occur only in a few tissues. Recent reports suggested that such post-translational protein modifications may occur in all tissues and proteins in vivo, including serum. For proof of concept using comprehensive analysis, the MS-based proteomic approach is straightforward; however, the isomerization of Asp has not been involved in proteomics studies because of no change in molecular weight. Here, we show a novel strategy, isoAsp-Quest, a database search-oriented large-scale isoAsp identification method.

ORGANISM(S): Bos Taurus

SUBMITTER: Hiroaki Sakaue

PROVIDER: PXD051863 | JPOST Repository | Wed Apr 30 00:00:00 BST 2025

REPOSITORIES: jPOST

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			Action	DRS
	Crystallin_alkylation_trypsin.csv	Csv
	Crystallin_alkylation_trypsin.raw	Raw
	Crystallin_alkylation_trypsin_AspN.csv	Csv
	Crystallin_alkylation_trypsin_AspN.raw	Raw
	Crystallin_alkylation_trypsin_AspN_PIMT.csv	Csv

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