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Posttranslational modification analysis of Histone H3t

ABSTRACT: Comprehensive posttranslational modifications in the testis-specific histone variant H3t protein validated in tagged knock-in mice.

ORGANISM(S): Mus Musculus (mouse)

SUBMITTER: Jun Ueda

PROVIDER: PXD052428 | JPOST Repository | Fri Sep 13 00:00:00 BST 2024

REPOSITORIES: jPOST

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			Action	DRS
	SN230256_H3-WT.mgf	Mgf
	SN230256_H3-WT.mzid	Mzid
	SN230256_H3-WT_1ul.raw	Raw
	SN230257_H3t-Flag.mgf	Mgf
	SN230257_H3t-Flag.mzid	Mzid

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Publications

Comprehensive posttranslational modifications in the testis-specific histone variant H3t protein validated in tagged knock-in mice.

Kawaguchi Takayuki T Hashimoto Michihiro M Nakagawa Reiko R Minami Ryunosuke R Ikawa Masahito M Nakayama Jun-Ichi JI Ueda Jun J

Scientific reports 20240912 1

During the development of multicellular organisms and cell differentiation, the chromatin structure in the cell nucleus undergoes extensive changes, and the nucleosome structure is formed by a combination of various histone variants. Histone variants with diverse posttranslational modifications are known to play crucial roles in different regulatory functions. We have previously reported that H3t, a testis-specific histone variant, is essential for spermatogenesis. To elucidate the function of t ...[more]

PMID: 39266663

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