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Proteomic analysis of human eosinophils stimulated with NOD2 ligand and IL-5

ABSTRACT: Activated eosinophils are a major cell type involved in allergic diseases. IL-5 primarily activates eosinophils and prolongs their survival. However, interactions between these cells and microorganisms are also important for further activation. NOD2 (Nucleotide-binding oligomerization domain-containing protein 2) is an intracellular pattern recognition receptor that plays a key role in the immune system. It recognizes muramyl dipeptide (MDP), a component of bacterial cell walls. The aim of this study is to clarify the role of NOD2 as a key receptor for human eosinophil activation.

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Jun Miyata

PROVIDER: PXD052647 | JPOST Repository | Thu May 29 00:00:00 BST 2025

REPOSITORIES: jPOST

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			Action	DRS
	PK23017-07_Q-N.mzML	Mzml
	PK23017-07_Q-N.raw	Raw
	PK23017-08_Q-5.mzML	Mzml
	PK23017-08_Q-5.raw	Raw
	PK23017-09_Q-5-M.mzML	Mzml

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