Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Proteomic and phosphoproteomic profiling revealed distinct cellular responses during Tilapia Lake Virus infection

ABSTRACT: Tilapia Lake Virus (TiLV) poses a significant threat to global tilapia aquaculture, causing high mortality rates and severe economic losses. Despite its impact, the molecular mechanisms of TiLV-host interactions remain poorly understood. This study investigates the proteomic and phosphoproteomic changes in two piscine cell lines, E-11 and RHTiB, following TiLV infection.

ORGANISM(S): Cellular Organisms

SUBMITTER: Tuchakorn Lertwanakarn

PROVIDER: PXD053604 | JPOST Repository | Wed Sep 25 00:00:00 BST 2024

REPOSITORIES: jPOST

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	P-E11_1hr-1_1.mzXML	Mzxml
	P-E11_1hr-1_2.mzXML	Mzxml
	P-E11_1hr-1_3.mzXML	Mzxml
	P-E11_1hr-2_1.mzXML	Mzxml
	P-E11_1hr-2_2.mzXML	Mzxml

Items per page:

1 - 5 of 20

Similar Datasets

ADAPTATION TO HYDROSTATIC PRESSURE SHAPES PROTEOME DYNAMICS IN CORROSIVE SULFATE-REDUCING BACTERIA

Project description:Microbially influenced corrosion (MIC) poses a major threat to metal structures across various industries, resulting in substantial economic losses and environmental risks. As deep-sea exploration expands, understanding MIC under high hydrostatic pressure becomes increasingly critical. Microorganisms in these extreme environments undergo distinct structural and metabolic adaptations to survive and thrive. In this study, we employed a proteomic approach to examine the lifestyle and corrosive potential of two sulfate-reducing bacteria (SRB) species with different pressure optima under simulated depths ranging from the sea surface to 3000 meters. Species-specific corrosion mechanisms and unique proteomic signatures associated with pressure adaptation were identified, correlating with opposing trends in corrosion rates. Our findings emphasize the need to characterize microbial physiology in relation to environmental conditions to better predict corrosion risks in extreme deep-sea settings.

2025-03-04 | PXD061434 | JPOST Repository

Dynamic and systemic regulation occurs in the liver of rainbow trout (Oncorhynchus mykiss) in response to environmental hypoxia

Project description:The hypoxia frequently occurs in natural aquatic systems and aquaculture environment due to the natural reasons and human factors such as extreme climate, high density farming, environmental pollution and global warming, which have gradually become a huge threat to aquatic ecosystem functions and aquatic organism survival, causing serious ecological damage and enormous economic losses. Rainbow trout (Oncorhynchus mykiss), as a hypoxia-sensitive fish species, is a good model to study hypoxia stress. The molecular regulation and oxidative stress of rainbow trout still remains unknown in response to environmental hypoxia and reoxygenation stress. In this study, the transcriptome and biochemical indexes of rainbow trout liver in response to hypoxia for different durations were analyzed to highlight the changes in the molecular regulation and oxidative stress.

2021-02-25 | GSE167386 | GEO

Quantitative proteomics based on TMT revealed the response of PK15 cells infected PEDV wild strain

Project description:Porcine epidemic diarrhea (PED), caused by porcine epidemic diarrhea virus (PEDV), is an acute and contagious enteric disease with high mortality in sucking piglets, causing huge economic losses to swine industry. In this study, we used tandem mass tag (TMT) quantitative protein analysis to investigate the proteomic changes of PK15 cells after PEDV infection, and the differential protein expression profiles were obtained at 0 h, 24 h, and 48 h after PEDV infection

2023-11-13 | PXD046881 |

Transcriptome Analyses Reveal Molecular Responses of Three Potato (Solanum tuberosum L.) Cultivars to Cold Stress

Project description:Potato (Solanum tuberosum L.), as an important food crop on the Qinghai-Tibet Plateau, is prone to low temperature and frost damage during the seedling stage, causing economic losses for farmers. In this study, transcriptome analyses were conducted on the leaves of Atlantic, KY130 and KY140 potato varieties following exposure to cold stress (CS). The genes StPAL(Soltu.Atl.09_2G005110) and StGAD(Soltu.Atl.11_3G000340), suggesting their involvement in the regulation of cold resistance in potato. “Flavonoid-related metabolism,” “lipid metabolism,” “amino acid metabolism,” “carbohydrate metabolism,” “nucleotide metabolism,” and “energy metabolism” might play an important role in the cold resistance of potato. Our results provided novel insights into the molecular mechanisms underlying cold resistance in potato.

2025-03-12 | GSE291340 | GEO

SnRNA-seq of pancreas revealed the dysfunction of endocrine and exocrine cells in transgenic pig with prediabetes

Project description:Diabetes poses a tremendous threat to human health. Exocrine pancreatic dysfunction is related to diabetes, but the exact mechanism is not fully understood. In this study, the high-fat and high-sucrose dietary interventions were performed on diabetes susceptible transgenic pigs (PIGinH11) and wild pigs. And the molecular mechanism of pancreatic endocrine and exocrine damage was analyzed by histopathology and single nucleus RNA sequencing.

2023-04-22 | GSE226141 | GEO

Dual RNA-seq analysis of pig alveolar macrophage infected with china-isolated TgHB1 compared to TgRH and TgMe49 toxoplasma gondii standard strain

Project description:Toxoplasma gondii is an apicomplexan parasite infecting human and animals, causing huge health concerns and economic losses. However, it is unclear about the exact mechanism of T.gondii tachyzoite infected macrophage and macrophage resisted T.gondii, especially for local isolates such as TgHB1 isolated in China. Our study focused on the transcriptional difference of pig alveolar macrophages (3D4/21) infected with china isolated TgHB1 compared to TgRH and TgME49 toxoplasma gondii standard strains.

2020-09-12 | GSE153330 | GEO

Mutation Mapping of Streptococcus suis serotype 2 strains

Project description:Streptococcus suis serotype 2 (SS2), an important zoonotic agent, is notorious for causing contagious porcine diseases and human infection. The two outbreaks in China (in 1998 and in 2005) have caused serious economic losses in the pig industry and posed public health for its new toxin shock symptoms (TSS). However, the molecular mechanism of SS2 pathogenicity is still poorly understood. In order to get insights into pathogenecity of SS2, eighteen SS2 strains of different virulence and sources have been subjected to whole genome comparison by NimbleGen CGS arrays Comparative genomic analysis of 18 SS2 strains with 05ZYH33 as reference

2009-08-29 | E-GEOD-17868 | biostudies-arrayexpress

Responses to infectious pancreatic necrosis virus (IPNV) in the liver of Atlantic salmon

Project description:IPNV is a viral pathogen causing losses in commercial aquaculture of Atlantic salmon. This study was performed to examine transcriptomic responses to IPNV and to compare them with changes caused with other viruses.

2021-04-22 | GSE172862 | GEO

Proteome analysis of Mycobacterium fortuitum biofilm

Project description:Biofilm formation by the environmental and clinical contaminant Mycobacterium fortuitum causes economic losses and serious threat to human health, as a consequence of its increasing contribution to nosocomial infections. There are no reports that elucidate physiological adaptations taking place during its planktonic to biofilm transition. The present study was hence carried out considering the global proteome of the mycobacterium. This is the first description of a global proteomic investigation into M. fortuitum biofilm. Scrutiny of biological functions in the two states provided insights into the phenotypic switch, and fundamental pathways associated with M. fortuitum pathobiology.

2023-09-11 | PXD023784 | Pride

TEST TEST Biofilm formation by the environmental and clinical contaminant Mycobacterium fortuitum causes economic losses and serious TEST TEST TEST

2022-06-04 | PXD023528 | Pride