Zc3h13 promotes T cell activation through snoRNA-mediated ribosome biogenesis

ABSTRACT: To test hypothesis that Zc3h13 regulates the translation of a subset of mRNAs critical for T cell activation, we performed quantitative profiling of nascent peptides in TCR-stimulated T cells using puromycin incorporation and SILAC labeling-based nascent polypeptidome profiling (pSNAP).

ORGANISM(S): Mus Musculus (mouse)

SUBMITTER: Osamu Takeuchi 

PROVIDER: PXD061567 | JPOST Repository | Sat Mar 07 00:00:00 GMT 2026

REPOSITORIES: jPOST