Proteomic changes in canine serum during natural estrus
Ontology highlight
ABSTRACT: Key findings include upregulated proteins during anestrus, such as HES2 and ADGRA3, associated with tissue maintenance and hormonal responsiveness, and DNA repair proteins safeguarding genomic stability. In proestrus, LIMK1 supported cytoskeletal reorganization, while estrus highlighted proteins like Polycystin Family Receptor for Egg Jelly and TEX14, potentially involved in sperm-egg interaction and germ cell communication. Diestrus featured proteins like ANGPTL7 and SLC7A1, supporting vascular remodeling and nutrient transport for pregnancy. Unique patterns, such as OR4Q3B upregulation in anestrus and estrus and OVGP1 downregulation in estrus, suggest complex reproductive signaling
ORGANISM(S): Cellular Organisms
SUBMITTER: Theerawat Tharasanit
PROVIDER: PXD063293 | JPOST Repository | Sat Apr 25 00:00:00 BST 2026
REPOSITORIES: jPOST
ACCESS DATA