Proteomics

Dataset Information

0

Unveiling BCL-xL-specific PROTAC Efficiency and Dissociation Mechanisms Using Native Mass Spectrometry


ABSTRACT: Native mass spectrometry enabled direct confirmation of PROTAC-mediated targeting of BCL-xL, while auxiliary activation methods dissected the disassembly of the ternary complexes, offering mechanistic insights.

ORGANISM(S): Escherichia Coli

SUBMITTER: Jennifer S. Brodbelt 

PROVIDER: PXD071449 | JPOST Repository | Sun Feb 15 00:00:00 GMT 2026

REPOSITORIES: jPOST

Dataset's files

Source:
Action DRS
10uMBCL-xL_10uM_753.RAW Raw
10uMVCB_10uMVH032_MS1.RAW Raw
10uMVCB_10uMVH298_MS1.RAW Raw
BCL-xL_753b_DT2216_10uM.RAW Raw
BCL-xL_PZ32644_10uM.RAW Raw
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