Proteomics

Dataset Information

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Screening pertactin-specific antibodies and evaluating competitive epitope recognition by native mass spectrometry


ABSTRACT: This study employs high-resolution native mass spectrometry (nMS) to define, compare, and mechanistically dissect the binding behavior of four therapeutic monoclonal antibodies (1E7, 2B1, 1F2, and 2E9) targeting the Bordetella pertussis antigen pertactin (Prn).

ORGANISM(S): Escherichia Coli Mus Musculus (mouse)

SUBMITTER: Jennifer S. Brodbelt 

PROVIDER: PXD071705 | JPOST Repository | Fri Feb 13 00:00:00 GMT 2026

REPOSITORIES: jPOST

Dataset's files

Source:
Action DRS
1E7_2B1_Prn_Competition%20experiment.RAW Raw
1E7_Prn_vT.RAW Raw
1E7_mAb_vT.RAW Raw
1F2_1E7_Prn_Competition%20experiment.RAW Raw
1F2_2B1_Prn_Competition%20experiment.RAW Raw
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