Dataset Information

Proteomic analyses of squamous components in two- and three-dimensional-cultured pancreatic ductal adenocarcinoma cell lines

ABSTRACT: This study aimed to analyze ductal and squamous marker expression in pancreatic ductal adenocarcinoma (PDAC) cell lines under two-dimensional (2D) and three-dimensional (3D) culture conditions. Eight PDAC cell lines were examined using nanoLC-MS/MS-based proteomics.

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Toshiyuki Ishiwata

PROVIDER: PXD073878 | JPOST Repository | Sun Feb 01 00:00:00 GMT 2026

REPOSITORIES: jPOST

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Dataset's files

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			Action	DRS
	PaC_Exp6-7_240223_500ng_95min_N3_01_PK-8_Ad.pdResult	Other
	PaC_Exp6-7_240223_500ng_95min_N3_01_PK-8_Ad.pdResultView	Other
	PaC_Exp6-7_240223_500ng_95min_N3_02_PK-45P_Ad.pdResult	Other
	PaC_Exp6-7_240223_500ng_95min_N3_02_PK-45P_Ad.pdResultView	Other
	PaC_Exp6-7_240223_500ng_95min_N3_03_PK-59_Ad.pdResult	Other

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Publications

Proteomic and immunocytochemical analyses of squamous components in two- and three-dimensional-cultured pancreatic ductal adenocarcinoma cell lines.

Shichi Yuuki Y Tsumoto Hiroki H Fujiwara Masakazu M Nonaka Keisuke K Hasegawa Yasuko Y Shinji Seiichi S Rokutan Hirofumi H Takahashi Kimimasa K Arai Tomio T Miura Yuri Y Ishiwata Toshiyuki T

Oncology letters 20260319 5

Adenosquamous carcinoma of the pancreas consists of both adenocarcinoma and squamous cell carcinoma components and shows a worse prognosis compared with pancreatic ductal adenocarcinoma (PDAC). Given that squamous cells are absent in healthy pancreatic tissue, their origin in pancreatic tumors remains unclear. The present study aimed to analyze ductal and squamous marker expression in PDAC cell lines under two-dimensional (2D) and three-dimensional (3D) culture conditions. A total of eight PDAC ...[more]

PMID: 41918815

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