Dataset Information
IScience 2026 splitTurboID APMS and GFP IPMS datasets
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Laura Trinkle-Mulcahy
PROVIDER: PXD074243 | JPOST Repository | Fri Feb 20 00:00:00 GMT 2026
REPOSITORIES: jPOST
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| DP1061_NIPP1_SILAC_Maxquant.zip | Other | |||
| DP1061_RRP1B_SILAC_Maxquant.zip | Other | |||
| DP1061_RawFiles_NIPP1_SILAC.zip | Other | |||
| DP1061_RawFiles_RRP1B_SILAC.zip | Other | |||
| DP1063_NOM1_SILAC_Maxquant.zip | Other |
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Publications
SplitTurboID mapping of dimeric protein phosphatase complex interactomes.
iScience 20260228 4
Unlike its counterpart Ser/Thr kinases, the predominant Ser/Thr protein phosphatase 1 (PP1) is a promiscuous enzyme that gains its subcellular localization and substrate specificity from a large panel of regulatory proteins with which it associates. Mapping the interactomes of catalytic and regulatory subunits on their own provides evidence for the targeting of PP1 to a wide range of cellular pathways, but does not provide a conditional analysis of individual holophosphatase complexes. To achiev ...[more]
