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Proteomic analysis of nonsmall cell lung cancer

ABSTRACT: These data correspond to PMID: 22761400, "In-depth proteomic analysis of nonsmall cell lung cancer to discover molecular targets and candidate biomarkers." (Mol Cell Proteomics. 2012 Oct;11(10):916-32. Epub 2012 Jul 3.)

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Daniel C. Liebler

PROVIDER: MSV000078491 | MassIVE | Mon Nov 18 14:33:00 GMT 2013

REPOSITORIES: MassIVE

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In-depth proteomic analysis of nonsmall cell lung cancer to discover molecular targets and candidate biomarkers.

Kikuchi Takefumi T Hassanein Mohamed M Amann Joseph M JM Liu Qinfeng Q Slebos Robbert J C RJ Rahman S M Jamshedur SM Kaufman Jacob M JM Zhang Xueqiong X Hoeksema Megan D MD Harris Bradford K BK Li Ming M Shyr Yu Y Gonzalez Adriana L AL Zimmerman Lisa J LJ Liebler Daniel C DC Massion Pierre P PP Carbone David P DP

Molecular & cellular proteomics : MCP 20120703 10

Advances in proteomic analysis of human samples are driving critical aspects of biomarker discovery and the identification of molecular pathways involved in disease etiology. Toward that end, in this report we are the first to use a standardized shotgun proteomic analysis method for in-depth tissue protein profiling of the two major subtypes of nonsmall cell lung cancer and normal lung tissues. We identified 3621 proteins from the analysis of pooled human samples of squamous cell carcinoma, aden ...[more]

PMID: 22761400

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