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Human colorectal cancer CPTAC dataset

ABSTRACT: This is a same data set generated by Vanderbilt University. 6M spectra was generated from 95 colorectal cancer samples. We used SpliceDB tool to generate a customized database which includes novel / alternative splice junction and small SNV information.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Vineet Bafna

PROVIDER: MSV000079166 | MassIVE | Thu Jun 18 13:32:00 BST 2015

REPOSITORIES: MassIVE

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Publications

Advanced Proteogenomic Analysis Reveals Multiple Peptide Mutations and Complex Immunoglobulin Peptides in Colon Cancer.

Woo Sunghee S Cha Seong Won SW Bonissone Stefano S Na Seungjin S Tabb David L DL Pevzner Pavel A PA Bafna Vineet V

Journal of proteome research 20150721 9

Aiming toward an improved understanding of the regulation of proteins in cancer, recent studies from the Clinical Proteomic Tumor Analysis Consortium (CPTAC) have focused on analyzing cancer tissue using proteomic technologies and workflows. Although many proteogenomics approaches for the study of cancer samples have been proposed, serious methodological challenges remain, especially in the identification of multiple mutational variants or structural variations such as fusion gene events. In add ...[more]

PMID: 26139413

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