Global identification of biofilm-specific proteolysis in Candida albicans

ABSTRACT: The global extracellular protease substrate specificity of C. albicans under biofilm and planktonic (suspension) conditions was determined with a synthetic library of 14-mer peptide substrates using an approach termed Multiplex Substrate Profiling by Mass Spectrometry (MSP-MS). Shotgun proteomics analysis on conditioned media from C. albicans grown under biofilm and planktonic conditions was performed to identify the corresponding proteases.

INSTRUMENT(S): LTQ Orbitrap XL

ORGANISM(S): Candida Albicans (ncbitaxon:5476)

SUBMITTER: Clarissa J. Nobile 

PROVIDER: MSV000079564 | MassIVE | Wed Mar 09 15:40:00 GMT 2016

REPOSITORIES: MassIVE