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Human DNA Mismatch Repair pathway LC-MSMS

ABSTRACT: The mismatch repair (MMR) family is a highly conserved group of proteins that function in correcting base-base and insertion-deletion mismatches generated during DNA replication. To systematically investigate the mismatch repair pathway, we conducted a proteomic analysis and identified MMR-associated protein complexes using a tandem-affinity purification coupled with mass spectrometry (TAP-MS) method. In total, we identified 262 high-confidence candidate interaction proteins (HCIPs).

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Dr Junjie Chen

PROVIDER: MSV000079578 | MassIVE | Sun Mar 13 17:31:00 GMT 2016

SECONDARY ACCESSION(S): PXD003014

REPOSITORIES: MassIVE

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