Off-target responses in the HeLa proteome subsequent to transient plasmid transfection using SILAC

ABSTRACT: We report a significant differential expression of proteins, all of which are associated with a viral infection response typified by Interferon type I/II. Notably the upregulated proteins may affect several vital cellular processes, including cell cycle control, translation and post-translational modification of proteins.

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Dr Geir Slupphaug 

PROVIDER: MSV000079757 | MassIVE | Mon May 23 12:46:00 BST 2016

SECONDARY ACCESSION(S): PXD001278

REPOSITORIES: MassIVE