Extracellular Matrix Analysis of Human Varicose Veins
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER: Dr Manuel Mayr
PROVIDER: MSV000080062 | MassIVE | Wed Aug 17 18:21:00 BST 2016
SECONDARY ACCESSION(S): PXD002555
REPOSITORIES: MassIVE
Publications
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Barallobre-Barreiro Javier J Oklu Rahmi R Lynch Marc M Fava Marika M Baig Ferheen F Yin Xiaoke X Barwari Temo T Potier David N DN Albadawi Hassan H Jahangiri Marjan M Porter Karen E KE Watkins Michael T MT Misra Sanjay S Stoughton Julianne J Mayr Manuel M
Cardiovascular research 20160411 3
<h4>Aims</h4>Extracellular matrix remodelling has been implicated in a number of vascular conditions, including venous hypertension and varicose veins. However, to date, no systematic analysis of matrix remodelling in human veins has been performed.<h4>Methods and results</h4>To understand the consequences of venous hypertension, normal and varicose veins were evaluated using proteomics approaches targeting the extracellular matrix. Varicose saphenous veins removed during phlebectomy and normal ...[more]
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