Detergent Resistant Memebrane Proteome of Plasmodium Berghei trophozoites and gametocytes
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ XL ETD
ORGANISM(S): Plasmodium Berghei Anka (ncbitaxon:5823)
SUBMITTER: Ponzi M.
PROVIDER: MSV000080108 | MassIVE | Wed Aug 31 09:44:00 BST 2016
REPOSITORIES: MassIVE
Publications
An Integrated Approach to Explore Composition and Dynamics of Cholesterol-rich Membrane Microdomains in Sexual Stages of Malaria Parasite.
Fratini Federica F Raggi Carla C Sferra Gabriella G Birago Cecilia C Sansone Anna A Grasso Felicia F Currà Chiara C Olivieri Anna A Pace Tomasino T Mochi Stefania S Picci Leonardo L Ferreri Carla C Di Biase Antonella A Pizzi Elisabetta E Ponzi Marta M
Molecular & cellular proteomics : MCP 20170810 10
Membrane microdomains that include lipid rafts, are involved in key physiological and pathological processes and participate in the entry of endocellular pathogens. These assemblies, enriched in cholesterol and sphingolipids, form highly dynamic, liquid-ordered phases that can be separated from the bulk membranes thanks to their resistance to solubilization by nonionic detergents. To characterize complexity and dynamics of detergent-resistant membranes of sexual stages of the rodent malaria para ...[more]
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