Parkinson's disease mouse brain proteome profiling
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Mus Musculus (ncbitaxon:10090)
SUBMITTER: 
Sung Jung
PROVIDER: MSV000080437 | MassIVE | Sun Dec 25 20:45:00 GMT 2016
SECONDARY ACCESSION(S): PXD005626
REPOSITORIES: MassIVE
Publications
An Anatomically Resolved Mouse Brain Proteome Reveals Parkinson Disease-relevant Pathways.
Jung Sung Yun SY Choi Jong Min JM Rousseaux Maxime W C MW Malovannaya Anna A Kim Jean J JJ Kutzera Joachim J Wang Yi Y Huang Yin Y Zhu Weimin W Maity Suman S Zoghbi Huda Yahya HY Qin Jun J
Molecular & cellular proteomics : MCP 20170202 4
Here, we present a mouse brain protein atlas that covers 17 surgically distinct neuroanatomical regions of the adult mouse brain, each less than 1 mm<sup>3</sup> in size. The protein expression levels are determined for 6,500 to 7,500 gene protein products from each region and over 12,000 gene protein products for the entire brain, documenting the physiological repertoire of mouse brain proteins in an anatomically resolved and comprehensive manner. We explored the utility of our spatially define ...[more]
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Project description:This a model from the article:
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The original CellML model was created by:
Catherine Lloyd
c.lloyd@auckland.ac.nz
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This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team.
To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication
for more information.
In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not..
To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
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This model was taken from the CellML repository
and automatically converted to SBML.
The original model was:
Benson AP, Aslanidi OV, Zhang H, Holden AV. (2008) - version=1.0
The original CellML model was created by:
Catherine Lloyd
c.lloyd@auckland.ac.nz
The University of Auckland
This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team.
To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication
for more information.
In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not..
To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
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Benson AP, Aslanidi OV, Zhang H, Holden AV. Prog Biophys Mol Biol
2008 Jan-Apr;96(1-3):187-208 17915298
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We have constructed computational models of canine ventricular cells and
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Hund-Rudy canine cell model in order to reproduce experimentally reported
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cells. These models are validated against experimental data for individual ionic
current and action potential characteristics, and their rate dependencies. 1D
and 3D heterogeneous virtual tissues are constructed, with detailed tissue
architecture (anisotropy and orthotropy, due to fibre orientation and sheet
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This suggests an electrophysiological mechanism for the anti- and proarrhythmic
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hence, a narrow vulnerable window and low probability of re-entry in the tissue.
This model was taken from the CellML repository
and automatically converted to SBML.
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Benson AP, Aslanidi OV, Zhang H, Holden AV. (2008) - version=1.0
The original CellML model was created by:
Catherine Lloyd
c.lloyd@auckland.ac.nz
The University of Auckland
This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team.
To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication
for more information.
In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not..
To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
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