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Optimization of a heterologous pathway for protocatechuate catabolism in Escherichia coli

ABSTRACT: Optimization of a heterologous pathway for protocatechuate catabolism in Escherichia coli

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Escherichia Coli (ncbitaxon:562)

SUBMITTER: Joshua K. Michener

PROVIDER: MSV000081122 | MassIVE | Tue May 30 13:48:00 BST 2017

SECONDARY ACCESSION(S): PXD006627

REPOSITORIES: MassIVE

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Construction and Optimization of a Heterologous Pathway for Protocatechuate Catabolism in Escherichia coli Enables Bioconversion of Model Aromatic Compounds.

Clarkson Sonya M SM Giannone Richard J RJ Kridelbaugh Donna M DM Elkins James G JG Guss Adam M AM Michener Joshua K JK

Applied and environmental microbiology 20170831 18

The production of biofuels from lignocellulose yields a substantial lignin by-product stream that currently has few applications. Biological conversion of lignin-derived compounds into chemicals and fuels has the potential to improve the economics of lignocellulose-derived biofuels, but few microbes are able both to catabolize lignin-derived aromatic compounds and to generate valuable products. While <i>Escherichia coli</i> has been engineered to produce a variety of fuels and chemicals, it is i ...[more]

PMID: 28733280

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