EMI_TB_PROTEOMICS_CSIC
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap, Orbitrap Fusion
ORGANISM(S): Human
SUBMITTER: 
Monica Carrera
PROVIDER: MSV000081574 | MassIVE | Mon Oct 02 01:42:00 BST 2017
REPOSITORIES: MassIVE
Publications
High-resolution quantitative proteomics applied to the study of the specific protein signature in the sputum and saliva of active tuberculosis patients and their infected and uninfected contacts.
Mateos Jesús J Estévez Olivia O González-Fernández África Á Anibarro Luis L Pallarés Ángeles Á Reljic Rajko R Gallardo José M JM Medina Isabel I Carrera Mónica M
Journal of proteomics 20190118
Our goal was to establish panels of protein biomarkers that are characteristic of patients with microbiologically confirmed pulmonary tuberculosis (TB) and their contacts, including latent TB-infected (LTBI) and uninfected patients. Since the first pathogen-host contact occurs in the oral and nasal passages the saliva and sputum were chosen as the biological fluids to be studied. Quantitative shotgun proteomics was performed using a LTQ-Orbitrap-Elite platform. For active TB patients, both fluid ...[more]
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