Proteomic analysis reveals multiple targets of tankyrase-mediated degradation

ABSTRACT: To identify targets of tankyrase 1 and 2 we established a double knock out HEK293T cell line. We compared the proteins in WT versus the double knock out applying a relative quantitation method using TMT tags and off-line fractionation of the proteome.

INSTRUMENT(S): Orbitrap Fusion ETD

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Beatrix Ueberheide  

PROVIDER: MSV000081663 | MassIVE | Thu Nov 02 09:46:00 GMT 2017

SECONDARY ACCESSION(S): PXD008117

REPOSITORIES: MassIVE