Ceritinib Functional Proteomics

ABSTRACT: To elucidate the mechanism of action (MoA) of ceritinib’s antiproliferative activity in these cells, we applied a systems approach combining both chemical and phosphoproteomics to gain a global view of ceritinib’s target profile and network-wide phosphorylation changes following ceritinib treatment.

INSTRUMENT(S): LTQ Orbitrap, Q Exactive

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Uwe Rix  

PROVIDER: MSV000081935 | MassIVE | Sat Jan 13 11:14:00 GMT 2018

SECONDARY ACCESSION(S): PXD007137

REPOSITORIES: MassIVE