Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Proteomics analysis of phage phiR201 infecting Yersinia enterocolitica

ABSTRACT: DDA analysis of phage phiR201 infecting Yersinia enterocolitica using the six-frame translated viral genome as a sequence database

INSTRUMENT(S): Q Exactive

ORGANISM(S): Yersinia Phage Phir201 (ncbitaxon:1206557)

SUBMITTER: Lotta Happonen

PROVIDER: MSV000082215 | MassIVE | Tue Mar 27 13:19:00 BST 2018

SECONDARY ACCESSION(S): PXD009347

REPOSITORIES: MassIVE

ACCESS DATA

Json Xml

Similar Datasets

Proteomic analysis of Yersinia enterocolitica phage phiR201

Project description:DDA analysis of phage phiR201 infecting Yersinia enterocolitica using the Uniprot proteomes UP000002908 and UP000000642 as sequence database

2018-03-27 | MSV000082214 | MassIVE

Whole transcriptome sequencing of phage φR1-37 and its host Yersinia enterocolitica

Project description:RNA-sequencing was preformed from RNA isolated from bacteria infected with the bacteriophage. In order to reveal the phage-host interactions between φR1-37 and Yersinia enterocolitica throughout the phage infection cycle, both the transcriptomes were scrutinized during all the stages of infection.

2016-01-22 | GSE77068 | GEO

Influence of the aminoglycoside antibiotic apramycin on host and phage DNA transcription during infection of S. venezuelae ATCC 10712 with phage Alderaan

Project description:Bacterial populations face the constant threat of viral predation exerted by bacteriophages (or phages). In response, bacteria have evolved a wide range of defense mechanisms against phage challenges. Here, we show that aminoglycosides, a well-known class of antibiotics produced by Streptomyces, are potent inhibitors of phage infection. We observed a broad phage inhibition by aminoglycosides. We demonstrate that aminoglycosides do not prevent the injection of phage DNA into bacterial cells but instead block an early step of the viral life cycle. In this context, we used RNA sequencing of S. venezuelae cells infected with phage Alderaan to comparatively investigate the influence of apramycin on phage DNA tanscription at two different time points after inital infection.

2021-04-30 | GSE171784 | GEO

Yersinia phage Yepe2

Project description:Yersinia phage Yepe2 overview

| PRJNA69755 | ENA

Comparative genomic hybridization of twenty four Salmonella enteritidis strains from six phage types

Project description:In this study differences at the genetic level of 24 S. Enteritidis strains from six phage types were compared using Comparative Genomic Hybridisation (CGH) DNA microarrays to determine why some certain phage types are 'less successful' in causing human infection.

2008-08-02 | E-MEXP-1720 | biostudies-arrayexpress

Type I CRISPR-Cas provides robust immunity but incomplete attenuation of phage-induced cellular stress

Project description:During infection, phages manipulate bacteria to redirect metabolism towards viral proliferation. To counteract phages, some bacteria employ CRISPR-Cas systems that provide adaptive immunity. While CRISPR-Cas mechanisms have been studied extensively, their effects on both the phage and the host during phage infection remains poorly understood. Here, we analysed the infection of Serratia by a siphovirus (JS26) and the transcriptomic response with, or without type I-E or I-F CRISPR-Cas immunity. In non-immune Serratia, phage infection altered bacterial metabolism by upregulating anaerobic respiration and amino acid biosynthesis genes, while flagella production was suppressed. Furthermore, phage proliferation required a late-expressed viral Cas4, which did not influence CRISPR adaptation. While type I-E and I-F immunity provided robust defence against phage infection, phage development still impacted the bacterial host. Moreover, DNA repair and SOS response pathways were upregulated during type I immunity. We also discovered that the type I-F system is controlled by a positive autoregulatory feedback loop that is activated upon phage targeting during type I-F immunity, leading to a controlled anti-phage response. Overall, our results provide new insight into phage-host dynamics and the impact of CRISPR immunity within the infected cell.

2021-10-28 | GSE186673 | GEO

Yersinia phage YeP4

Project description:Yersinia phage YeP4 Genome sequencing

| PRJNA530032 | ENA

Yersinia phage YeP5

Project description:Yersinia phage YeP5 Genome sequencing

| PRJNA530039 | ENA

Yersinia phage Yepe2

Project description:Yersinia phage Yepe2 Genome sequencing

| PRJNA29827 | ENA

Yersinia phage YeP6

Project description:Yersinia phage YeP6 Genome sequencing