Proteomics

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Alcohol-driven changes in fetal cerebral artery proteome


ABSTRACT: We conducted proteome analysis of basilar (cerebral) arteries from three control baboon fetuses and four fetuses that were exposed to alcohol in utero. Three alcohol-exposure episodes took place during second trimester-equivalent of human pregnancy, while fetal arteries were harvested during cesarean sections performed near-term. Supernatants from whole artery lysates were processed for TMT-labeling, fractionated, and subjected to LC/MS analysis.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Papio (ncbitaxon:9554)

SUBMITTER: Anna Bukiya  

PROVIDER: MSV000082291 | MassIVE | Thu Apr 19 06:49:00 BST 2018

SECONDARY ACCESSION(S): PXD009545

REPOSITORIES: MassIVE

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