Dataset Information
Delayed effect of early-life exposure to 17-alpha-ethinylestradiol on the liver proteome of adult mangrove rivulus fish
Ontology highlight
ABSTRACT:
INSTRUMENT(S): impact
ORGANISM(S): Kryptolebias Marmoratus (ncbitaxon:37003)
SUBMITTER: 
Frederic Silvestre Dietmar Kueltz
PROVIDER: MSV000082815 | MassIVE | Mon Aug 13 22:46:00 BST 2018
SECONDARY ACCESSION(S): PXD010765
REPOSITORIES: MassIVE
Publications
Early-life exposure to the endocrine disruptor 17-α-ethinylestradiol induces delayed effects in adult brain, liver and ovotestis proteomes of a self-fertilizing fish.
Journal of proteomics 20181212
Early-life represents a critically sensitive window to endocrine disrupting chemicals, potentially leading to long-term repercussions on the phenotype later in life. The mechanisms underlying this phenomenon, referred to as the Developmental Origins of Health and Disease (DOHaD), are still poorly understood. To gain molecular understanding of these effects, we exposed mangrove rivulus (Kryptolebias marmoratus) for 28 days post hatching (dph) to 4 and 120 ng/L 17-α-ethinylestradiol, a model xenoe ...[more]
