Covalent Protein Painting in AD

ABSTRACT: The 3D structures of aberrant protein folds have been visualized in detail in vitro, yet no method has been able to quantitatively measure protein misfolding across a proteome in vivo. Covalent protein painting is a mass spectrometry-based structural proteomics approach to quantify the protein surface accessibility at select amino acid residues in vivo.

INSTRUMENT(S): Orbitrap Fusion Lumos, LTQ Orbitrap Velos, Orbitrap Fusion

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: John R. Yates III  

PROVIDER: MSV000083031 | MassIVE | Fri Oct 12 12:28:00 BST 2018

SECONDARY ACCESSION(S): PXD011351

REPOSITORIES: MassIVE