Proteomics

Dataset Information

0

PProteomic analysis of enhanced cellular effects of electroporation and cisplatin in triple-negative breast cancer cells


ABSTRACT: We performed a comprehensive and label-free quantitative proteomic analysis of the human adenocarcinoma epithelial TNBC cells (MDA-MB-231) treated with Cisplatin (CsP) and Cisplatin with EP (EP+CsP). We identified hundreds of differentially expressed proteins that defines molecular mechanisms involved in cellular responses of MDA-MB-231 cells to ECT. The underlying dataset represents a valuable resource for mechanistic studies and for the validation of knowledge gained from this study in the future using animal models. The systemic data should build a foundation for a better understanding of the mechanisms of the cytotoxicity of the Cisplatin as a potent anticancer drug.

INSTRUMENT(S): Q Exactive Orbitrap HF mass spectrometer

ORGANISM(S): Mda-mb-231 Tnbc Model Cells

SUBMITTER: Rajeswari Sundararajan  

PROVIDER: MSV000083360 | MassIVE | Thu Jan 24 14:07:00 GMT 2019

REPOSITORIES: MassIVE

Similar Datasets

2022-06-20 | GSE178310 | GEO
2022-06-20 | GSE178307 | GEO
2022-06-20 | GSE178305 | GEO
2021-09-22 | ST001920 | MetabolomicsWorkbench
2023-03-20 | PXD040990 | iProX
2019-08-16 | PXD013833 | Pride
2018-09-04 | GSE119377 | GEO
2021-11-29 | GSE163900 | GEO
2012-03-01 | E-GEOD-33827 | biostudies-arrayexpress
2022-03-03 | GSE191066 | GEO