Proteomic Time-Course Investigation into the Effects of Exposure of Mycobacterium smegmatis to Sub-Lethal Dose of Rifampicin

ABSTRACT: Drug susceptible Mycobacterium smegmatis (Mc2-155) was exposed to a sub-MIC concentration of antimycobacterial drug Rifampicin (treated) or DMSO (control). Cells were harvested at 30, 255 and 300 minutes post-exposure and the proteome at each time analysed using LC-MS/MS on a Thermo Q-Exactive.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mycobacterium Smegmatis Str. Mc2 155 (ncbitaxon:246196)

SUBMITTER: Jonathan M Blackburn  

PROVIDER: MSV000083589 | MassIVE | Mon Mar 18 06:09:00 GMT 2019

SECONDARY ACCESSION(S): PXD004197

REPOSITORIES: MassIVE