Analysis of brain and cerebrospinal fluid from mouse models of the three major forms of neuronal ceroid lipofuscinosis reveals changes in the lysosomal proteome.
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ABSTRACT: Purified mannose-6 phosphate glycoproteins from brain of mouse NCL models.
Project description:TMT10plex analysis of whole brain extracts from mouse models of CLN1, CLN2 and CLN3 by MS3 reporter ion measurement conducted on Thermo Fusion Lumos Tribrid.