Proteomics

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Multi-omics analysis of plasma in atrial fibrillation patients


ABSTRACT: Comprehensive metabolomic and proteomic analyses reveal candidate biomarkers and related metabolic networks in atrial fibrillation.

INSTRUMENT(S): Q-Exactive HF

ORGANISM(S): Homo sapiens  

SUBMITTER: Juntuo Zhou  

PROVIDER: MSV000083774 | MassIVE | Tue May 14 03:40:00 BST 2019

REPOSITORIES: MassIVE

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Publications

Comprehensive metabolomic and proteomic analyses reveal candidate biomarkers and related metabolic networks in atrial fibrillation.

Zhou Juntuo J   Sun Lijie L   Chen Liwen L   Liu Shuwang S   Zhong Lijun L   Cui Ming M  

Metabolomics : Official journal of the Metabolomic Society 20190621 7


INTRODUCTION:Atrial fibrillation (AF) is an abnormal heart rhythm characterized by an irregular beating of the atria and is associated with an increased risk of heart failure, dementia, and stroke. Currently, the perturbation of plasma content due to AF disease onset is not well known. OBJECTIVES:To investigate dysregulated molecules in blood plasma of untreated AF patients, with the goal of identifying biomarkers for disease screening and pathological studies. METHODS:LC-MS based untargeted met  ...[more]

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