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Mouse tooth injury 21d IL4KO vs WT

ABSTRACT: 1234567980 1234567980 1234567980 1234567980 1234567980 1234567980 1234567980

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

SUBMITTER: Octavio Luiz Franco

PROVIDER: MSV000083799 | MassIVE | Sat May 18 13:25:00 BST 2019

SECONDARY ACCESSION(S): PXD013910

REPOSITORIES: MassIVE

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Publications

IL-4 absence triggers distinct pathways in apical periodontitis development.

Freire Mirna S MS Oliveira Nelson G NG Lima Stella M F SMF Porto William F WF Martins Danilo C M DCM Silva Osmar N ON Chaves Sacha B SB Sousa Marcelo V MV Ricart Carlos A O CAO Castro Mariana S MS Fontes Wagner W Franco Octavio L OL Rezende Taia M B TMB

Journal of proteomics 20201215

Dental pulp is a specialized tissue able to respond to infectious processes. Nevertheless, infection progress and root canal colonization trigger an immune-inflammatory response in tooth-surrounding tissues, leading to apical periodontitis and bone tissue destruction, further contributing to tooth loss. In order to shed some light on the effects of IL-4 on periradicular pathology development modulation, microtomographic, histological and proteomic analyses were performed using 60 mice, 30 wild t ...[more]

PMID: 33338687

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